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| Chemical Analysis Published TOHO 1994 page 136 |
Kaushal Kumar, Vinod Upadhyay
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"Savitri Pharmacueticals” no longer existed . However one of its erstwhile partner had floated & started a new company naming it as “HARSHUL AYUR PHARMA” in the year 2006, which has been granted a license to manufacture ayurvedic medicine/drugs. " |
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The recipe was prepared form C. medica (auran.) juice, which was first boiled, in order to coagulate and precipitate protein like matter and then neutralized with a requisite weight of Sarjika and Cypraea moneta at 30o C. Recipe takes 5 days for its preparation. It was a white milky suspension.10.0 g. of the traditional drug suspension were taken in a silica crucible previously ignited, cooled and weighed. The sample were ashed in a muffle furnace at 600o C until the ash is free from carbon. The crucible was weighed after cooling.
Accurately weighed ash is moistend with a small amount of distilled water (0.5 ml). Then mixture was evaporated to dryness on a boiling water bath. Ash was again digested with 5.0 ml of hydrochloric acid near to dryness and 2.0 ml of hydrogen peroxide (analytical grade) was added. The digested material was diluted with deionised water in a 100 ml flask to the volume.
The sample ash solution, in suitable aliquots, was then used for various analytical determinations. The minerals Calcium, Sodium, Potassium, Magnesium, Iron, Phosphorus, Chloride, Sulphate were determined in accordance with standard methods (flame photo metric, spectro photo metric, volumetric and gravimetric methods) reported in the literature (12) .
The analytical data of the sample are given in Table 2. |
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Chemistry of Traditional Recipes Used in Hepatic Disorders |
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RESULTS OF PHYSICO-CHEMICAL CHARACTERISTICS OF TRADITIONAL RECIPE |
*Parameter
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Mean of three mg/ml. |
Parameter |
Mean of three mg/ml. |
1. Sodium |
6.5 |
13. Lose on drying at 100oC |
89.62% |
2. Potassium |
0.44 |
14. pH at 30oC
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3. Calcium |
5.4 |
(a) Ash Solution
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0.7 |
| 4. Magnesium |
3.29 |
(b) 10% Ash Solution
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1.4 |
| 5. Iron |
0.01 |
(c) 1% Ash Solution
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2.4 |
| 6. Chloride |
1.136 |
(d) Drug Suspension
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3.80 |
| 7. Sulphate |
0.160 |
(e) C. medica (auran.) Juice |
2.81 |
| 8. Phosphorus (Total) |
0.0134 |
Density of (susp.) |
1.03 g/ml |
| 9. Phosphorus (Inorganic) |
0.0104 |
Density of (Juice) |
0.975 g/m |
| 10. Phosphorus (Organic) |
0.003 |
Physical state |
Liquid suspension |
| 11. **Citric acid +ve |
test |
Colour |
White milky |
| 12. Ash Content (in 100 gm.) |
3.3470 gm. |
Taste |
Sour |
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| * At the initial stage, it may not be possible to find parameter for standardization, due to variation of constitutes of ingredients depending upon the season, place and purity etc. |
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| ** Aqueous extract of Traditional drug gives positives test of Citric acid. |
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RELATION BETWEEN VARIOUS DIGESTIVE JUICES AND TRADITIONAL RECIPE |
NAME
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DIGESTIVE JUICES (13) FUNCTION |
INORGANIC CONSTITUENTS |
RECIPE, INORGANIC CONSTITUENTS |
1. Intestinal Juice |
Wide stages digestion of carbo-hydrates, Proteins and fats. |
0.8% salts of Na,K,Ca and Mg with chloride Bicarbonate, Phosphate |
Traditional Recipe has also shown the presence of natural Na, K, Ca, Mg, Chloride, Phosphate etc. in varing amounts. |
2. Pancreatic Juice |
digestion of carbo-hydrates, Proteins and fats. |
High bicarbonate content, principal bases are Na, K, Small amounts of Ca, Mg and Zn. |
There is close relation between the inorganic constituents of Pancreatic Juice and recipe, the t. drug may accelerates metabolic function of pancreatic juice. |
3. Gastric Juice |
The enzyme pepsin with HCL, digests Proteins upto stage, of peptone HCL causes hydrolysis of food stuffs. |
0.15% NaCl,KCl,Calacium chloride & Phosphate, Magnesium Phosphate, Bicarbonate and HCl. |
The presence of inorganic salts of traditional drug may be responsible for enhancing the function f gastric juice in a natural way |
| 4. Saliva |
Wide stages, digestion of carbohydrates and many other mechanical functions. |
0.2% NaCl, KCl, acid and alkaline sodium phosphate,calcium carbonate, calcium phosphate, potassium thiocyanate etc. |
Fast acting ability of t. drug is attributed due to the presence of its common salts also indicated in the saliva. |
| 5. Bile |
It acts as a very important digestive juices, life cannot be maintained without it, essential for complete digestion of fats and some extend of protein, carbohydrates, action is due to the presence of bile salts |
Chlorides, Carbonates and Phosphate of Na, K and Ca and NaHCO3 etc. |
Traditional recipe has proved boon to the patients with liver ailments, it may be all due to the presence of inorganic salts of bile in the drug, which play very significant role for various metabolism and enhance the production and secretion |
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